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1

The Biology of Proteostasis in Aging and Disease

Labbadia, Johnathan, Morimoto, Richard I

Journal:

Annual Review of Biochemistry

Year:

2015

Language:

english

File:

PDF, 4.05 MB

english, 2015

2

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

Powers, Evan T., Morimoto, Richard I., Dillin, Andrew, Kelly, Jeffery W., Balch, William E.

Journal:

Annual Review of Biochemistry

Year:

2009

Language:

english

File:

PDF, 2.18 MB

english, 2009

3

Regulation of Organismal Proteostasis by Transcellular Chaperone Signaling

van Oosten-Hawle, Patricija, Porter, Robert S., Morimoto, Richard I.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.57 MB

english, 2013

4

Celastrol Analogues as Inducers of the Heat Shock Response. Design and Synthesis of Affinity Probes for the Identification of Protein Targets

Klaić, Lada, Morimoto, Richard I., Silverman, Richard B.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.95 MB

english, 2012

5

Proteostasis: monitoring the health of the proteome in biology, aging and disease

Morimoto, Richard

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 43 KB

english, 2013

6

Geroscience: Linking Aging to Chronic Disease

Kennedy, Brian K., Berger, Shelley L., Brunet, Anne, Campisi, Judith, Cuervo, Ana Maria, Epel, Elissa S., Franceschi, Claudio, Lithgow, Gordon J., Morimoto, Richard I., Pessin, Jeffrey E., Rando, Thom

Journal:

Year:

2014

Language:

english

File:

PDF, 468 KB

english, 2014

7

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

Walther, Dirk M., Kasturi, Prasad, Zheng, Min, Pinkert, Stefan, Vecchi, Giulia, Ciryam, Prajwal, Morimoto, Richard I., Dobson, Christopher M., Vendruscolo, Michele, Mann, Matthias, Hartl, F. Ulrich

Journal:

Year:

2015

Language:

english

File:

PDF, 3.04 MB

english, 2015

8

Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction

Labbadia, Johnathan, Morimoto, Richard I.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.28 MB

english, 2015

9

DIVISION X WORKING GROUP on HISTORIC RADIO ASTRONOMY

Orchiston, Wayne, Kellermann, Kenneth I., Davies, Rodney D., Débarbat, Suzanne V., Morimoto, Masaki, Slysh, Slava, Swarup, Govind, van Woerden, Hugo, Wall, Jasper V., Wielebinski, Richard

Journal:

Proceedings of the International Astronomical Union

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

10

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

Walther, Dirk M., Kasturi, Prasad, Zheng, Min, Pinkert, Stefan, Vecchi, Giulia, Ciryam, Prajwal, Morimoto, Richard I., Dobson, Christopher M., Vendruscolo, Michele, Mann, Matthias, Hartl, F. Ulrich

Journal:

Year:

2017

Language:

english

File:

PDF, 61 KB

english, 2017

11

The association between role model presence and self-regulation in early adolescence: A cross-sectional study

Nakanishi, Miharu, Yamasaki, Syudo, Endo, Kaori, Ando, Shuntaro, Morimoto, Yuko, Fujikawa, Shinya, Kanata, Sho, Takahashi, Yusuke, Furukawa, Toshi A., Richards, Marcus, Hiraiwa-Hasegawa, Mariko, Kasai

Journal:

Year:

2019

Language:

english

File:

PDF, 493 KB

english, 2019

12

Development and further characterization of a small subclass of rat olfactory receptor neurons that shows immunoreactivity for the HSP70 heat shock protein

McMillan Carr, Virginia, Morimoto, Richard I., Farbman, Albert I.

Journal:

The Journal of Comparative Neurology

Year:

1999

Language:

english

File:

PDF, 320 KB

english, 1999

13

Odorants as cell-type specific activators of a heat shock response in the rat olfactory mucosa

Virginian McMillan Carr, Bert Ph.M. Menco, Maya P. Yankova, Richard I. Morimoto, Albert I. Farbman

Journal:

The Journal of Comparative Neurology

Year:

2001

Language:

english

File:

PDF, 1.05 MB

english, 2001

14

Small subclass of rat olfactory neurons with specific bulbar projections is reactive with monoclonal antibodies to the HSP70 heat shock protein

Dr. Virginia McMillan Carr, Shawn P. Murphy, Richard I. Morimoto, Albert I. Farbman

Journal:

The Journal of Comparative Neurology

Year:

1994

Language:

english

File:

PDF, 1.34 MB

english, 1994

15

Caenorhabditis elegans as a model system to study intercompartmental proteostasis: Interrelation of mitochondrial function, longevity, and neurodegenerative diseases

Janine Kirstein-Miles, Richard I. Morimoto

Journal:

Developmental Dynamics

Year:

2010

Language:

english

File:

PDF, 263 KB

english, 2010

16

Cis-acting sequences and trans-acting factors required for constitutive expression of a microinjected HSP70 gene after the midblastula transition of Xenopus laevis embryogenesis

Nick Ovsenek, Gregg T. Williams, Richard I. Morimoto, Dr. John J. Heikkila

Journal:

Year:

1990

Language:

english

File:

PDF, 1.49 MB

english, 1990

17

The association of Na,K-ATPase subunits studied by circular dichroism, surface tension and dilatational elasticity

Carolina Fortes Rigos, Thatyane Morimoto Nobre, Maria Elisabete Darbello Zaniquelli, Richard John Ward, Pietro Ciancaglini

Journal:

Journal of Colloid and Interface Science

Year:

2008

Language:

english

File:

PDF, 236 KB

english, 2008

18

Controlled syntheses and structures of bimetallic complexes of two bidentate phosphine-phosphido ligands

Devon W. Meek, Robert Waid, Kwoliang D. Tau, Richard M. Kirchner, Carl N. Morimoto

Journal:

Inorganica Chimica Acta

Year:

1982

Language:

english

File:

PDF, 265 KB

english, 1982

19

Physical mapping of the yeast mitochondrial genome

Richard Morimoto, Murray Rabinowitz

Journal:

Molecular Genetics and Genomics

Year:

1979

Language:

english

File:

PDF, 1.88 MB

english, 1979

20

Physical mapping and characterization of the mitochondrial DNA and RNA sequences from mit-mutants defective in cytochrome oxidase peptide 1 (OXI 3)

Richard Morimoto, Alfred Lewin, Murray Rabinowitz

Journal:

Molecular Genetics and Genomics

Year:

1979

Language:

english

File:

PDF, 842 KB

english, 1979

21

Physical mapping of the Xba I, Hinc II, Bgl II, Xho I, Sst I, and Pvu II restriction endonuclease cleavage fragments of mitochondrial DNA ofS. cerevisiae

Richard Morimoto, Murray Rabinowitz

Journal:

Molecular Genetics and Genomics

Year:

1979

Language:

english

File:

PDF, 1.06 MB

english, 1979

22

Physical mapping of genes on yeast mitochondrial DNA: Localization of antibiotic resistance loci, and rRNA and tRNA genes

Richard Morimoto, Sylvie Merten, Alfred Lewin, Nancy C. Martin, Murray Rabinowitz

Journal:

Molecular Genetics and Genomics

Year:

1978

Language:

english

File:

PDF, 1.24 MB

english, 1978

23

Restriction enzyme analysis of mitochondrial DNAs of petite mutants of yeast: Classification of petites, and deletion mapping of mitochondrial genes

Alfred Lewin, Richard Morimoto, Murray Rabinowitz, Hiroshi Fukuhara

Journal:

Molecular Genetics and Genomics

Year:

1978

Language:

english

File:

PDF, 1.65 MB

english, 1978

24

Analysis of mitochondrial RNA inSaccharomyces cerevisiae

Joseph Locker, Richard Morimoto, Richard M. Synenki, Murray Rabinowitz

Journal:

Current Genetics

Year:

1980

Language:

english

File:

PDF, 1016 KB

english, 1980

25

Biochemical events in the activation and attenuation of the heat shock transcriptional response

Sanjeev H Satyal, Richard I Morimoto

Journal:

Journal of Biosciences

Year:

1998

Language:

english

File:

PDF, 1.23 MB

english, 1998

26

A simple mass-action model for the eukaryotic heat shock response and its mathematical validation

Ion Petre, Andrzej Mizera, Claire L. Hyder, Annika Meinander, Andrey Mikhailov, Richard I. Morimoto, Lea Sistonen, John E. Eriksson, Ralph-Johan Back

Journal:

Natural Computing

Year:

2011

Language:

english

File:

PDF, 642 KB

english, 2011

27

Arylsulfanyl pyrazolones block mutant SOD1-G93A aggregation. Potential application for the treatment of amyotrophic lateral sclerosis

Tian Chen, Radhia Benmohamed, Anthony C. Arvanites, Hantamalala Ralay Ranaivo, Richard I. Morimoto, Robert J. Ferrante, D. Martin Watterson, Donald R. Kirsch, Richard B. Silverman

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 541 KB

english, 2011

28

Role of the Heat-Shock Response in the Life and Death of Proteins

ANU MATHEW, RICHARD I. MORIMOTO

Journal:

Annals of the New York Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 913 KB

english, 1998

29

10.1038/35019501

Green, Douglas R., Beere, Helen M., Wolf, Beni B., Cain, Kelvin, Mosser, Dick D., Mahboubi, Artin, Kuwana, Tomomi, Tailor, Pankaj, Morimoto, Richard I., Cohen, Gerald M.

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 436 KB

english, 2000

30

10.1038/35060068

Song, Jaewhan, Takeda, Masahiro, Morimoto, Richard I.

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 855 KB

english, 2001

31

Stress–inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection

Morimoto, Richard I., Santoro, M.Gabriella

Journal:

Nature Biotechnology

Year:

1998

File:

PDF, 914 KB

1998

32

Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state

Kitamura, Akira, Kubota, Hiroshi, Pack, Chan-Gi, Matsumoto, Gen, Hirayama, Shoshiro, Takahashi, Yasuo, Kimura, Hiroshi, Kinjo, Masataka, Morimoto, Richard I., Nagata, Kazuhiro

Journal:

Nature Cell Biology

Year:

2006

Language:

english

File:

PDF, 3.82 MB

english, 2006

33

Polyglutamine protein aggregates are dynamic

Kim, Soojin, Nollen, Ellen A. A., Kitagawa, Kazunori, Bindokas, Vytautas P., Morimoto, Richard I.

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 930 KB

english, 2002

34

Heat shock factors: integrators of cell stress, development and lifespan

Åkerfelt, Malin, Morimoto, Richard I., Sistonen, Lea

Journal:

Nature Reviews Molecular Cell Biology

Year:

2010

Language:

english

File:

PDF, 603 KB

english, 2010

35

The life of proteins: the good, the mostly good and the ugly

Morimoto, Richard I, Driessen, Arnold J M, Hegde, Ramanujan S, Langer, Thomas

Journal:

Nature Structural and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

36

Inefficient degradation of truncated polyglutamine proteins by the proteasome

Holmberg, Carina I, Staniszewski, Kristine E, Mensah, Kwame N, Matouschek, Andreas, Morimoto, Richard I

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 572 KB

english, 2004

37

The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity

Morimoto, Alyssa M, Tomlinson, Michael G, Nakatani, Kaname, Bolen, Joseph B, Roth, Richard A, Herbst, Ronald

Journal:

Year:

2000

Language:

english

File:

PDF, 361 KB

english, 2000

38

Molecular chaperones and the stress of oncogenesis

Mosser, Dick D, Morimoto, Richard I

Journal:

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

39

Quantitation and Cloning of Human Urushiol Specific Peripheral Blood T-Cells: Isolation of Urushiol Triggered Suppressor T-Cells.

Kalish, Richard S., Morimoto, Chikao

Journal:

The Journal of Investigative Dermatology

Year:

1989

File:

PDF, 1.92 MB

1989

40

Pathophysiology of human paralytic rabies

Thiravat Hemachudha, Supaporn Wacharapluesadee, Erawady Mitrabhakdi, Henry Wilde, Kinjiro Morimoto, Richard A. Lewis

Journal:

Journal of NeuroVirology

Year:

2005

Language:

english

File:

PDF, 103 KB

english, 2005

41

BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release

Bimston, David, Song, Jaewhan, Winchester, David, Takayama, Shinichi, Reed, John C., Morimoto, Richard I.

Journal:

The EMBO Journal

Year:

1998

Language:

english

File:

PDF, 384 KB

english, 1998

42

Bistability Explains Threshold Phenomena in Protein Aggregation both In Vitro and In Vivo

Theodore R. Rieger, Richard I. Morimoto, Vassily Hatzimanikatis

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 224 KB

english, 2006

43

ADME-Guided Design and Synthesis of Aryloxanyl Pyrazolone Derivatives To Block Mutant Superoxide Dismutase 1 (SOD1) Cytotoxicity and Protein Aggregation: Potential Application for the Treatment of Amyotrophic Lateral Sclerosis

Chen, Tian, Benmohamed, Radhia, Kim, Jinho, Smith, Karen, Amante, Daniel, Morimoto, Richard I., Kirsch, Donald R., Ferrante, Robert J., Silverman, Richard B.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

44

Chromosomal location of human genes encoding major heat-shock protein HSP70

Gail Singer Harrison, Harry A. Drabkin, Fa -Ten Kao, Judith Hartz, Iris M. Hart, Ernest H. Y. Chu, Barbara J. Wu, Richard I. Morimoto

Journal:

Somatic Cell and Molecular Genetics

Year:

1987

Language:

english

File:

PDF, 1.34 MB

english, 1987

45

Generation of CD8 (T8) cytotoxic cells has a preferential requirement for CD4+2H4− inducer cells

Richard S. Kalish, Chikao Morimoto, Stuart F. Schlossman

Journal:

Cellular Immunology

Year:

1988

Language:

english

File:

PDF, 806 KB

english, 1988

46

Visualizing the motion area

Richard I. Morimoto

Journal:

Current Biology

Year:

1993

Language:

english

File:

PDF, 266 KB

english, 1993

47

Cyclohexane 1,3-diones and their inhibition of mutant SOD1-dependent protein aggregation and toxicity in PC12 cells

Wei Zhang, Radhia Benmohamed, Anthony C. Arvanites, Richard I. Morimoto, Robert J. Ferrante, Donald R. Kirsch, Richard B. Silverman

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 5.05 MB

english, 2012

48

Chaperone networks: Tipping the balance in protein folding diseases

Cindy Voisine, Jesper Søndergaard Pedersen, Richard I. Morimoto

Journal:

Neurobiology of Disease

Year:

2010

Language:

english

File:

PDF, 928 KB

english, 2010

49

A cellular perspective on conformational disease: the role of genetic background and proteostasis networks

Tali Gidalevitz, Elise A Kikis, Richard I Morimoto

Journal:

Current Opinion in Structural Biology

Year:

2010

Language:

english

File:

PDF, 438 KB

english, 2010

50

Integrating the stress response: lessons for neurodegenerative diseases from C. elegans

Veena Prahlad, Richard I. Morimoto

Journal:

Trends in Cell Biology

Year:

2009

Language:

english

File:

PDF, 849 KB

english, 2009